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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2047273Generated: October 30, 2026

N-Methylisobutylamine → 2-(Isobutyl-methyl-amino)-6-methyl-isonicotinic acid

https://huagongshe.com/reaction/2047273

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-MethylisobutylamineHCID 12249—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reactant2-(Dimethylamino)-6-methylpyridine-4-carboxylic acidHCID 17921347—
Product2-(Isobutyl-methyl-amino)-6-methyl-isonicotinic acidHCID 58418096—

Reaction Steps

The title compound is prepared in analogy to 2-dimethylamino-6-methyl-isonicotinic acid starting from 2-chloro-6-methyl-isonicotinic acid and using isobutyl-methyl-amine; LC-MS: tR=0.61 min, [M+H]+=223.10.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08592460B2
Source datasetuspto-grants-2013_11
ORD IDord-a68be34c48c74aef97a90d1bcdd5774d
Source noteuspto-grants-2013_11