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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2047278Generated: November 2, 2026

Morpholine → 2-Methyl-6-(morpholin-4-yl)isonicotinic acid

https://huagongshe.com/reaction/2047278

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
Reactant2,6-Dichloroisonicotinic acidHCID 94830—
Reactant2-(Diethylamino)-6-methylisonicotinic acidHCID 58418055—
Product2-Methyl-6-(morpholin-4-yl)isonicotinic acidHCID 68578126—

Reaction Steps

The title compound is prepared in analogy to 2-diethylamino-6-methyl-isonicotinic acid starting from 2,6-dichloro-isonicotinic acid and morpholine; LC-MS: tR=0.47 min, [M+1]+=223.08.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08592460B2
Source datasetuspto-grants-2013_11
ORD IDord-3b5a52dacf974329ad217890c408382a
Source noteuspto-grants-2013_11