p-Cyanobenzyl alcohol → HCID 178513316, compound

HRID 2047300Notes

Reaction equation

HRID 2047300 reaction equation
C(OC(=O)C[CH2:8][C:9]1[C:14](C)=[CH:13][C:12]([C:16](=[NH:19])[NH:17][OH:18])=[CH:11][C:10]=1C)(C)(C)C.[OH:22]CC1C=CC(C#N)=CC=1>>[OH:18][NH:17][C:16](=[NH:19])[C:12]1[CH:13]=[CH:14][C:9]([CH2:8][OH:22])=[CH:10][CH:11]=1

Participants

3

Reactant 2

HCID 160549p-Cyanobenzyl alcoholHCID 178426653HCID 178426653, compound

Product 1

HCID 178513316HCID 178513316, compound

Procedure

The title compound is prepared in analogy to 3-[4-(N-hydroxycarbamimidoyl)-2,6-dimethyl-phenyl]-propionic acid tert-butyl ester (step g) starting from 4-hydroxymethyl-benzonitrile; LC-MS: tR=0.21 min, [M+1]+=167.04.

Sources & evidence

ORD record
ord-0795424513e44b21a68bae4df1a7dc9d
Source dataset
uspto-grants-2013_11
Patent number
US08592460B2

Reaction notes

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