2-(Diethylamino)-6-methylisonicotinic acid → HCID 68580107, compound

HRID 2047338Notes

Reaction equation

HRID 2047338 reaction equation
[OH:1][NH:2][C:3](=[NH:12])[C:4]1[CH:9]=[CH:8][C:7]([CH2:10][OH:11])=[CH:6][CH:5]=1.[CH2:13]([N:15]([CH2:26][CH3:27])[C:16]1[CH:17]=[C:18]([CH:22]=[C:23]([CH3:25])[N:24]=1)[C:19](O)=O)[CH3:14]>>[CH2:26]([N:15]([CH2:13][CH3:14])[C:16]1[CH:17]=[C:18]([C:19]2[O:1][N:2]=[C:3]([C:4]3[CH:5]=[CH:6][C:7]([CH2:10][OH:11])=[CH:8][CH:9]=3)[N:12]=2)[CH:22]=[C:23]([CH3:25])[N:24]=1)[CH3:27]

Participants

3

Reactant 2

HCID 584180552-(Diethylamino)-6-methylisonicotinic acidHCID 178513316HCID 178513316, compound

Product 1

HCID 68580107HCID 68580107, compound

Procedure

The title compound is prepared in analogy to Example 5 starting from N-hydroxy-4-hydroxymethyl-benzamidine and 2-diethylamino-6-methyl-isonicotinic acid; LC-MS: tR=0.76 min; [M+1]+=339.11.

Sources & evidence

ORD record
ord-0966c4f1d88247b282b9a2cd92c79b24
Source dataset
uspto-grants-2013_11
Patent number
US08592460B2

Reaction notes

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