2-(Diethylamino)-6-methylisonicotinic acid → 2-{4-[5-(2-Diethylamino-6-methyl-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-phenyl}-ethanol

Participants

Reaction Steps

The title compound is prepared in analogy to Example 5 starting from N-hydroxy-4-(2-hydroxy-ethyl)-benzamidine and 2-diethylamino-6-methyl-isonicotinic acid; LC-MS: tR=1.07*min; [M+1]+=353.11; 1H NMR (CDCl3): δ 1.25 (t, J=6.8 Hz, 6H), 2.50 (s, 3H), 2.98 (t, J=6.3 Hz, 2H), 3.63 (q, J=7.0 Hz, 4H), 3.95 (q, J=6.0 Hz, 2H), 7.02 (s, 1H), 7.10 (s, 1H), 7.41 (d, J=7.5 Hz, 2H), 8.15 (d, J=7.5 Hz, 2H).

Provenance & Evidence