3-Amino-1,2-propanediol → HCID 58264345, compound

Participants

Reaction Steps

5 g of methyl oleat (commercially available under the trade name EDENOR®ME V05 from Cognis GmbH, MW 296) and 1.54 g of 3-amino-1,2-propanediol (MW 91.1, Sigma-Aldrich) were mixed together at 70° C. After addition of 100 mg of Novozym®435 (lipase B from Candida Antarctica, from Novozymes), the reaction was conducted during 24 h at 70° C. under moderate agitation and vacuum (250-300 mbars). The mixture was filtrated to remove the immobilized enzyme. The product of the reaction was analyzed by HPLC-DEDL, to give an area ratio of N-oleyl-(3 amino-1,2-propanediol)/substrates>83%. Thus N-oleyl-(3 amino-1,2-propanediol) is a substance according to formula (I), wherein R1=—(CH2)7—CH═CH—(CH2)7—CH3 and R2=CH2—OH

Provenance & Evidence