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HRID2047532

反应详情

EQUATION

反应方程式

HRID 2047532 的结构方程式

REACTANTS

反应物

3
结构：OB(O)c1cncnc1
HCID2795193

5-Pyrimidinylboronic acid

C4H5BN2O2

结构：Cc1ccc(B2OC(C)(C)C(C)(C)O2)c(C)n1
HCID21980034

2,6-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

C13H20BNO2

结构：C[C@@H]1CCCN1[C@H]1C[C@H](c2nc3ccc(Br)cc3s2)C1
HCID178461421

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc(-c2ccc3nc([C@H]4C[C@H](N5CCCCC5)C4)sc3c2)c(C)n1
HCID178423687

未命名化合物

PROCEDURE

实验过程

The title compound was prepared according to the procedure described in Example 1F, substituting the product of Example 44A for the product of Example 1E and substituting the product of Example 2A for pyrimidine-5-boronic acid. 1H NMR (500 MHz, CDCl3) δ ppm 8.02 (d, J=8.24 Hz, 1H) 7.76 (s, 1H) 7.47 (d, J=7.63 Hz, 1H) 7.40 (dd, J=8.54, 1.53 Hz, 1H) 7.08 (d, J=7.63 Hz, 1H) 3.83-3.92 (m, 1H) 3.42-3.53 (m, 1H) 2.92-3.04 (m, 1H) 2.62-2.74 (m, 3H) 2.60 (s, 3H) 2.50 (s, 3H) 2.08 (s, 4H) 1.71-1.83 (m, 4H) 1.50-1.61 (m, 2H). MS: (M+H)+=378.