Ammonia → HCID 62190987, compound

HRID 2047723Notes

Reaction equation

HRID 2047723 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([O:12][CH:13]([CH3:15])[CH3:14])[CH:10]=2)[N:5]=[CH:4][C:3]=1[C:16]([O:18][CH2:19][CH3:20])=[O:17].[NH3:21]>>[CH2:19]([O:18][C:16]([C:3]1[CH:4]=[N:5][C:6]2[C:11]([C:2]=1[NH2:21])=[CH:10][C:9]([O:12][CH:13]([CH3:15])[CH3:14])=[CH:8][CH:7]=2)=[O:17])[CH3:20]

Participants

3

Reactant 2

HCID 222AmmoniaHCID 28969934HCID 28969934, compound

Product 1

HCID 62190987HCID 62190987, compound

Procedure

Prepared as in Example 1a from ethyl 4-chloro-6-isopropoxyquinoline-3-carboxylate (Example 10b) and ammonia as an off white solid (75%). MS 275 (MH+.

Sources & evidence

ORD record
ord-cf1c02f293a1478bbb32171cffd4d7b0
Source dataset
uspto-grants-2013_11
Patent number
US08592592B2

Reaction notes

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