Dimethyl Sulfoxide → 1-{1-[2,5-Bis(methyloxy)-4-nitrophenyl]-4-piperidinyl}-4-(2-fluoroethyl)piperazine
Reaction equation
[CH3:37][S:38]([CH3:39])=[O:40].[Cl:1][c:2]1[cH:3][c:4]([O:13][CH3:14])[c:5]([N+:10](=[O:11])[O-:12])[cH:6][c:7]1[O:8][CH3:9].[F:21][CH2:22][CH2:23][N:24]1[CH2:25][CH2:26][N:27]([CH:30]2[CH2:31][CH2:32][NH:33][CH2:34][CH2:35]2)[CH2:28][CH2:29]1.[K+:15].[K+:16].[O-:17][C:18]([O-:19])=[O:20].[OH2:36]>>[c:2]1([N:33]2[CH2:32][CH2:31][CH:30]([N:27]3[CH2:26][CH2:25][N:24]([CH2:23][CH2:22][F:21])[CH2:29][CH2:28]3)[CH2:35][CH2:34]2)[cH:3][c:4]([O:13][CH3:14])[c:5]([N+:10](=[O:11])[O-:12])[cH:6][c:7]1[O:8][CH3:9]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-55a20a1b19c447448bb5351803f5f4ab
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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