Butyric Acid → HCID 66747135, compound

HRID 2047771Notes

Reaction equation

[CH2:1]([O:3][C:4]([C:6]1[C:7]([CH3:25])=[N:8][C:9]2[C:14]([C:15]=1[NH2:16])=[C:13]([O:17][CH2:18][CH:19]1[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1)[CH:12]=[CH:11][CH:10]=2)=[O:5])[CH3:2].[C:26](O)(=[O:30])[CH2:27][CH2:28][CH3:29]>>[CH2:1]([O:3][C:4]([C:6]1[C:7]([CH3:25])=[N:8][C:9]2[C:14]([C:15]=1[NH2:16])=[C:13]([O:17][CH2:18][CH:19]1[CH2:20][CH2:21][N:22]([C:26](=[O:30])[CH2:27][CH2:28][CH3:29])[CH2:23][CH2:24]1)[CH:12]=[CH:11][CH:10]=2)=[O:5])[CH3:2]

Participants

Reactant 2

HCID 264Butyric Acid

HCID 66745973HCID 66745973, compound

Product 1

HCID 66747135HCID 66747135, compound

Procedure

Prepared as in Example 24a from ethyl-4-amino-2-methyl-5-(piperidin-4-ylmethoxy)-quinoline-3-carboxylate (Example 35b) and butyric acid as a yellow oil (50%). MS 414 (MH+).

Sources & evidence

ORD record: ord-f7fd151a8a124ac2b128e9c8f64d5098
Source dataset: uspto-grants-2013_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08592592B2

Reaction notes

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