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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2047799Generated: November 1, 2026

2-Amino-6-fluorobenzonitrile → 3-(3-amino-2-cyanophenoxy)-N-(3-methoxybenzyl)-2,2-dimethylpropanamide

https://huagongshe.com/reaction/2047799

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-6-fluorobenzonitrileHCID 522659—
Reactant3-hydroxy-N-(3-methoxybenzyl)-2,2-dimethylpropanamideHCID 66746123—
Product3-(3-amino-2-cyanophenoxy)-N-(3-methoxybenzyl)-2,2-dimethylpropanamideHCID 66746970—

Reaction Steps

Prepared as in Example 22b from 3-hydroxy-N-(3-methoxybenzyl)-2,2-dimethylpropanamide (Example 46c) and 2-amino-6-fluorobenzonitrile as a white solid (41%). MS 354 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08592592B2
Source datasetuspto-grants-2013_11
ORD IDord-4729d7e53e0442ca8695942cee30b546
Source noteuspto-grants-2013_11