2-Amino-6-fluorobenzonitrile → HCID 66745752, compound

HRID 2047831Notes

Reaction equation

HRID 2047831 reaction equation
[NH2:1][C@@H:2]([CH:5]([CH3:7])[CH3:6])[CH2:3][OH:4].[NH2:8][C:9]1[CH:16]=[CH:15][CH:14]=[C:13](F)[C:10]=1[C:11]#[N:12]>>[NH2:8][C:9]1[CH:16]=[CH:15][CH:14]=[C:13]([O:4][CH2:3][C@@H:2]([NH2:1])[CH:5]([CH3:7])[CH3:6])[C:10]=1[C:11]#[N:12]

Participants

3

Reactant 2

HCID 5226592-Amino-6-fluorobenzonitrileHCID 640993L-Valinol

Product 1

HCID 66745752HCID 66745752, compound

Procedure

Prepared as in Example 24d from (S)-2-amino-3-methylbutan-1-ol and 2-amino-6-fluorobenzonitrile as brown solid (71%). MS 220 (MH+).

Sources & evidence

ORD record
ord-63ac576fa1db46c8b8fea02633e4bf7c
Source dataset
uspto-grants-2013_11
Patent number
US08592592B2

Reaction notes

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