2-Amino-1-butanol, (+)- → HCID 66745584, compound

HRID 2047835Notes

Reaction equation

HRID 2047835 reaction equation
[NH2:1][C@@H:2]([CH2:5][CH3:6])[CH2:3][OH:4].[NH2:7][C:8]1[CH:15]=[CH:14][CH:13]=[C:12](F)[C:9]=1[C:10]#[N:11]>>[NH2:7][C:8]1[CH:15]=[CH:14][CH:13]=[C:12]([O:4][CH2:3][C@@H:2]([NH2:1])[CH2:5][CH3:6])[C:9]=1[C:10]#[N:11]

Participants

3

Reactant 2

HCID 1200842-Amino-1-butanol, (+)-HCID 5226592-Amino-6-fluorobenzonitrile

Product 1

HCID 66745584HCID 66745584, compound

Procedure

Prepared as in Example 24d from (S)-2-aminobutan-1-ol and 2-amino-6-fluorobenzonitrile as brown solid (73%). MS 206 (MH+).

Sources & evidence

ORD record
ord-2a55686e475e4363a05841900a248f43
Source dataset
uspto-grants-2013_11
Patent number
US08592592B2

Reaction notes

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