HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Benzodioxane-6-carboxylic Acid → (S)-ethyl 4-amino-5-(2-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamido) butoxy)-2-methylquinoline-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Benzodioxane-6-carboxylic Acid | HCID 2758833 | — |
| Reactant | (S)-ethyl 4-amino-5-(2-aminobutoxy)-2-methylquinoline-3-carboxylate | HCID 86658218 | — |
| Product | (S)-ethyl 4-amino-5-(2-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamido) butoxy)-2-methylquinoline-3-carboxylate | HCID 86658224 | — |
Reaction Steps
Prepared as in Example 24a from (S)-ethyl 4-amino-5-(2-aminobutoxy)-2-methylquinoline-3-carboxylate (Example 97b) and 2,3-dihydrobenzo[b][1,4]dioxine-6-carboxylic acid as brown solid (46%). MS 480 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08592592B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-8d93187e8982457dabb5e25eca486769 |
| Source note | uspto-grants-2013_11 |