3-Hydroxybenzoic Acid → HCID 66746923, compound

HRID 2047853Notes

Reaction equation

HRID 2047853 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[C:7]([CH3:25])=[N:8][C:9]2[C:14]([C:15]=1[NH2:16])=[C:13]([O:17][CH2:18][CH:19]1[CH2:24][CH2:23][CH2:22][CH2:21][NH:20]1)[CH:12]=[CH:11][CH:10]=2)=[O:5])[CH3:2].[OH:26][C:27]1[CH:28]=[C:29]([CH:33]=[CH:34][CH:35]=1)[C:30](O)=[O:31]>>[CH2:1]([O:3][C:4]([C:6]1[C:7]([CH3:25])=[N:8][C:9]2[C:14]([C:15]=1[NH2:16])=[C:13]([O:17][CH2:18][CH:19]1[CH2:24][CH2:23][CH2:22][CH2:21][N:20]1[C:30](=[O:31])[C:29]1[CH:33]=[CH:34][CH:35]=[C:27]([OH:26])[CH:28]=1)[CH:12]=[CH:11][CH:10]=2)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 74203-Hydroxybenzoic AcidHCID 66746461HCID 66746461, compound

Product 1

HCID 66746923HCID 66746923, compound

Procedure

Prepared as in Example 24a from ethyl-4-amino-2-methyl-5-(piperidin-2-ylmethoxy)-quinoline-3-carboxylate (Example 111b) and 3-hydroxybenzoic acid as a white solid (28%). MS 464 (MH+).

Sources & evidence

ORD record
ord-3a7333e8a9e64666a8247e2ac88bc6c2
Source dataset
uspto-grants-2013_11
Patent number
US08592592B2

Reaction notes

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