Piperidin-2-ylmethanol → HCID 66746947, compound

HRID 2047855Notes

Reaction equation

HRID 2047855 reaction equation
[NH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH:2]1[CH2:7][OH:8].[NH2:9][C:10]1[CH:17]=[CH:16][CH:15]=[C:14](F)[C:11]=1[C:12]#[N:13]>>[NH2:9][C:10]1[CH:17]=[CH:16][CH:15]=[C:14]([O:8][CH2:7][CH:2]2[CH2:3][CH2:4][CH2:5][CH2:6][NH:1]2)[C:11]=1[C:12]#[N:13]

Participants

3

Reactant 2

HCID 94263Piperidin-2-ylmethanolHCID 5226592-Amino-6-fluorobenzonitrile

Product 1

HCID 66746947HCID 66746947, compound

Procedure

Prepared as in Example 24d from 2-piperidinemethanol and 2-amino-6-fluoro-benzonitrile as a light yellow solid (64%). MS 232 (MH+).

Sources & evidence

ORD record
ord-15619b4e3d714595a5876d0b66680d84
Source dataset
uspto-grants-2013_11
Patent number
US08592592B2

Reaction notes

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