4-Pyridinemethanamine → HCID 66747256, compound

HRID 2047868Notes

Reaction equation

HRID 2047868 reaction equation
[NH2:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][C:10]=2[O:12][CH2:13][C:14]([CH3:19])([CH3:18])[C:15]([OH:17])=O)[N:5]=[C:4]([CH3:20])[C:3]=1[C:21]([O:23][CH2:24][CH3:25])=[O:22].[N:26]1[CH:31]=[CH:30][C:29]([CH2:32][NH2:33])=[CH:28][CH:27]=1>>[CH2:24]([O:23][C:21]([C:3]1[C:4]([CH3:20])=[N:5][C:6]2[C:11]([C:2]=1[NH2:1])=[C:10]([O:12][CH2:13][C:14]([CH3:18])([CH3:19])[C:15](=[O:17])[NH:33][CH2:32][C:29]1[CH:30]=[CH:31][N:26]=[CH:27][CH:28]=1)[CH:9]=[CH:8][CH:7]=2)=[O:22])[CH3:25]

Participants

3

Reactant 2

HCID 773174-PyridinemethanamineHCID 667468783-((4-Amino-3-(ethoxycarbonyl)-2-methylquinolin-5-yl)oxy)-2,2-dimethylpropanoic acid

Product 1

HCID 66747256HCID 66747256, compound

Procedure

Prepared as in Example 24a from 3-((4-amino-3-(ethoxycarbonyl)-2-methylquinolin-5-yl)oxy)-2,2-dimethylpropanoic acid (Example 47b) and pyridin-4-ylmethanamine as a brown solid (43%). MS 437 (MH+).

Sources & evidence

ORD record
ord-120b9cd5130f48979871c823aea7f4b2
Source dataset
uspto-grants-2013_11
Patent number
US08592592B2

Reaction notes

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