(-)-Menthol → HCID 66746507, compound

HRID 2047872Notes

Reaction equation

HRID 2047872 reaction equation
[CH:1]([C@@H:4]1[CH2:9][CH2:8][C@@H:7]([CH3:10])[CH2:6][C@H:5]1[OH:11])([CH3:3])[CH3:2].[NH2:12][C:13]1[CH:20]=[CH:19][CH:18]=[C:17](F)[C:14]=1[C:15]#[N:16]>>[NH2:12][C:13]1[CH:20]=[CH:19][CH:18]=[C:17]([O:11][C@@H:5]2[CH2:6][C@H:7]([CH3:10])[CH2:8][CH2:9][C@H:4]2[CH:1]([CH3:3])[CH3:2])[C:14]=1[C:15]#[N:16]

Participants

3

Reactant 2

HCID 16666(-)-MentholHCID 5226592-Amino-6-fluorobenzonitrile

Product 1

HCID 66746507HCID 66746507, compound

Procedure

Prepared as in Example 22b from (1R,2S,5R)-2-isopropyl-5-methylcyclohexanol and 2-amino-6-fluorobenzonitrile as a white solid (51%). MS 273 (MH+).

Sources & evidence

ORD record
ord-193025e4d06f4c8983730a4d2e820df8
Source dataset
uspto-grants-2013_11
Patent number
US08592592B2

Reaction notes

Loading…