HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminopyrimidine → 4-Imidazo[1,2-a]pyrimidin-2-ylbenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminopyrimidine | HCID 7978 | — |
| Reactant | HCID 17755522 | HCID 17755522 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 4-Imidazo[1,2-a]pyrimidin-2-ylbenzaldehyde | HCID 14042794 | — |
Reaction Steps
4-(bromoacetyl)benzaldehyde is dissolved in acetone. To it is added pyrimidin-2-amine (1 eq). The reaction mixture is stirred overnight. The precipitated solid is filtered off and dried to obtain the desired compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08592591B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-bc7e6e630171439db5b0776a98992e82 |
| Source note | uspto-grants-2013_11 |