Methyl 3-(benzyloxy)-5-[4-(methanesulfonyl)phenoxy]benzoate → Methyl 3-hydroxy-5-(4-(methylsulfonyl)phenoxy)benzoate

Participants

Reaction Steps

Methyl 3-(phenylmethyl)oxy-5-[4-(methylsulfonyl)phenoxy]benzoate (3.50 g, 8.50 mmol) was dissolved in THF (60 mL) followed by 10% palladium on carbon (500 mg). The reaction was then placed under a hydrogen atmosphere by an evacuation-backfill technique. The reaction was then stirred vigorously for 4 h followed by filtration and evaporation which afforded the title compound as an colourless oil (2.75 g, 100%).

Provenance & Evidence