HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → o-Nitrophenylacetyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | (2-Nitrophenyl)acetic acid | HCID 77337 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | o-Nitrophenylacetyl chloride | HCID 140956 | — |
Reaction Steps
Thionylchloride (12.0 g) and 18.11 g of 2-nitrophenylacetic acid are weighed into a flask and allowed to stand at room temperature (~21°) for 16 hours. A stirring bar is added and the reaction driven to completion by warming at 35° for five additional hours until no solid is visible. To the red solution is added 5 ml benzene and the volatile material is removed with vacuum to give 2-nitrophenyacetyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04196294 |
| Source dataset | uspto-grants-1980_04 |
| ORD ID | ord-2dcb9ad8a8334a258dd781639fb808e5 |
| Source note | uspto-grants-1980_04 |