4-Amino-5-chloro-2-methoxybenzoic acid → HCID 12861929, compound

HRID 2049193Notes

Reaction equation

HRID 2049193 reaction equation
[NH2:1][C:2]1[C:10]([Cl:11])=[CH:9][C:5]([C:6]([OH:8])=O)=[C:4]([O:12][CH3:13])[CH:3]=1.[NH2:14][CH2:15][CH:16]1[CH2:20][CH2:19][CH:18]([CH3:21])[N:17]1[CH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[CH2:22]([N:17]1[CH:18]([CH3:21])[CH2:19][CH2:20][CH:16]1[CH2:15][NH:14][C:6](=[O:8])[C:5]1[CH:9]=[C:10]([Cl:11])[C:2]([NH2:1])=[CH:3][C:4]=1[O:12][CH3:13])[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1

Participants

3

Reactant 2

HCID 816264-Amino-5-chloro-2-methoxybenzoic acidHCID 12861925HCID 12861925, compound

Product 1

HCID 12861929HCID 12861929, compound

Procedure

By following general method B using 1.01 g. of 4-amino-5-chloro-2-methoxybenzoic acid and 1.0 g. of 2-aminomethyl-1-benzyl-5-methylpyrrolidine, 1.5 g. of N-(1-benzyl-5-methyl-2-pyrrolidinyl-methyl)-4-amino-5-chloro-2-methoxybenzamide was obtained.

Sources & evidence

ORD record
ord-233802a5f8954f149723ad16265682d3
Source dataset
uspto-grants-1980_04
Patent number
US04197243

Reaction notes

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