Acetic Acid → 1,4-Bis[2-(3-hydroxypropylamino)ethylamino]-5,8-dihydroxyanthraquinone diacetate salt

HRID 2049205Notes

Reaction equation

HRID 2049205 reaction equation
[OH:1][CH2:2][CH2:3][CH2:4][NH:5][CH2:6][CH2:7][NH:8][C:9]1[C:22]2[C:21](=[O:23])[C:20]3[C:15](=[C:16]([OH:25])[CH:17]=[CH:18][C:19]=3[OH:24])[C:14](=[O:26])[C:13]=2[C:12]([NH:27][CH2:28][CH2:29][NH:30][CH2:31][CH2:32][CH2:33][OH:34])=[CH:11][CH:10]=1.[C:35]([OH:38])(=[O:37])[CH3:36]>C(O)C>[C:35]([OH:38])(=[O:37])[CH3:36].[C:35]([OH:38])(=[O:37])[CH3:36].[OH:1][CH2:2][CH2:3][CH2:4][NH:5][CH2:6][CH2:7][NH:8][C:9]1[C:22]2[C:21](=[O:23])[C:20]3[C:15](=[C:16]([OH:25])[CH:17]=[CH:18][C:19]=3[OH:24])[C:14](=[O:26])[C:13]=2[C:12]([NH:27][CH2:28][CH2:29][NH:30][CH2:31][CH2:32][CH2:33][OH:34])=[CH:11][CH:10]=1

Participants

4

Reactant 2

HCID 176Acetic AcidHCID 1531601,4-Bis[2-(3-hydroxypropylamino)ethylamino]-5,8-dihydroxyanthraquinone

Product 1

HCID 867369161,4-Bis[2-(3-hydroxypropylamino)ethylamino]-5,8-dihydroxyanthraquinone diacetate salt

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 228 mg. of 1,4-bis[2-(3-hydroxypropylamino)ethylamino]-5,8-dihydroxyanthraquinone, 60 mg. of glacial acetic acid, and 50 ml. of ethanol is heated under reflux for 30 minutes to give the title compound.

Workup

  1. additionA mixture of 228 mg
  2. temperatureunder reflux for 30 minutes

Sources & evidence

ORD record
ord-acce5fe4fde5484db242b7889f148100
Source dataset
uspto-grants-1980_04
Patent number
US04197249

Reaction notes

Loading…