Carbonodithioic acid, O-ethyl ester → (-)-alpha-Amino-3-[[(ethoxythioxomethyl)thio]methyl]-4-hydroxybenzeneacetic acid

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Reaction Steps

To a solution of (-)-α-amino-3-(chloromethyl)-4-hydroxybenzeneacetic acid hydrochloride (1 g, 0.004 mole) in 20 ml of water is added carbonodithioic acid, O-ethyl ester, potassium salt (1.26 g, 0.08 mole). Within a few minutes a precipitate begins to form. The mixture is stirred at room temperature for 3 hours. The solid precipitate is filtered, washed with water and dried to give 58.3% of the title compound.

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