Water → HCID 20345011, compound

HRID 2049281Notes

Reaction equation

HRID 2049281 reaction equation
C(OO)(=[O:3])C.[Cl:6][C:7]1[C:17]([O:18][C:19]2[CH:24]=[CH:23][C:22]([Cl:25])=[CH:21][C:20]=2[Cl:26])=[CH:16][C:10]2[N:11]=[C:12]([S:14][CH3:15])[NH:13][C:9]=2[CH:8]=1.[OH2:27]>C(O)(=O)C>[Cl:6][C:7]1[C:17]([O:18][C:19]2[CH:24]=[CH:23][C:22]([Cl:25])=[CH:21][C:20]=2[Cl:26])=[CH:16][C:10]2[N:11]=[C:12]([S:14]([CH3:15])(=[O:3])=[O:27])[NH:13][C:9]=2[CH:8]=1

Participants

5

Reactant 3

HCID 962WaterHCID 6585Peracetic AcidHCID 13373882HCID 13373882, compound

Product 1

HCID 20345011HCID 20345011, compoundYield 89%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

122 5 ml of 40% strength peracetic acid are added dropwise in the course of 30 minutes to a solution, which is kept at room temperature by cooling, of 100 g of 5-chloro-6-(2',4'-dichlorophenoxy)-2-methylthiobenzimidazole in 800 ml of glacial acetic acid, with stirring. The resulting dark red solution is stirred for a further 15 hours at room temperature. A viscous suspension forms and 4 l of demineralised water are added to this. The precipitate formed is then filtered off with suction, washed with water and dried in vacuo at 50° C. This gives 96 g of 5-chloro-6-(2',4'-dichlorophenoxy)-2-methylsulphonylbenzimidazole with a melting point of 215°-218° C., which corresponds to a yield of 89%.

Workup

  1. customis kept at room temperature
  2. stirringThe resulting dark red solution is stirred for a further 15 hours at room temperature
  3. customThe precipitate formed
  4. filtrationis then filtered off with suction
  5. washwashed with water
  6. customdried in vacuo at 50° C

Sources & evidence

ORD record
ord-8067f2725e574c469f5b90b6e9c50e6b
Source dataset
uspto-grants-1980_04
Patent number
US04197307

Reaction notes

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