Chloral → 1-[[4-amino-6-[(2,2,2-trichloro-1-hydroxyethyl)amino]-1,3,5-triazin-2-yl]amino]-2,2,2-trichloroethanol

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Reaction Steps

This compound has previously been prepared by Bump and Atkinson [J. Am Chem. Soc., 72, 629 (1950)]. Melamine (44.2 g, 0.3 mole) was added all at once to a stirred solution of chloral (221.2 g, 1.5 mole) dissolved in 375 ml. of water at 70°-80° C. The reaction mixture was stirred for 3 hours and the white precipitated product was filtered to give an 81% yield after drying. The product had a melting point >200° C. and decomposed on further heating.

Provenance & Evidence