Hydroxylamine → HCID 86736927, compound

Participants

Reaction Steps

3α-Acetoxy-17,17-ethylenedioxy-5α-androstan-11-one (1.0 g) was added to a solution of hydroxylamine prepared by addition of 50% aqueous sodium hydroxide (4 ml) to hydroxylamine hydrochloride (2 g) in ethanol (30 ml). After 17 hours reflux most of the solvent was evaporated in vacuo, the residue was diluted with water and the solid (836 mg) was collected by filtration. A portion was recrystallized from aqueous ethanol to afford the title compound m.p. 158°-159°.

Provenance & Evidence