Phenethyl bromide → HCID 20343899, compound

Participants

Reaction Steps

Samples of 10,11-dihydro-11-oxospiro[dibenz(b,f)oxepin-10,4'-piperidine], free base of Example 3, are separately treated with phenoxypropyl bromide and 2-bromoethylbenzene according to the procedure of Example 12, to provide colorless prisms, mp 213°-215° C., (dec), of 10,11-dihydro-11-oxo-1'-(3-phenoxypropyl)-spiro[dibenz(b,f)oxepin-10,4'-piperidine]hydrobromide (from an ethyl alcohol-ether mixture), Example 13, and colorless prisms, mp>300° C., of 10,11-dihydro-11-oxo-1'-phenethylspiro[dibenz(b,f)-oxepin-10,4'-piperidine]hydrobromide (from an acetone-ether mixture), Example 14, respectively.

Provenance & Evidence