Dimethylamine → 2-Dimethylamino-1-isopropyl-1-pyrrolinium methyl sulfate

HRID 2049650노트

반응식

HRID 2049650 반응식
[CH3:1][O:2][S:3]([O-:6])(=[O:5])=[O:4].[CH:7]([N+:10]1[CH2:14][CH2:13][CH2:12][C:11]=1OC)([CH3:9])[CH3:8].[CH3:17][NH:18][CH3:19]>C1C=CC=CC=1>[CH3:1][O:2][S:3]([O-:6])(=[O:5])=[O:4].[CH3:17][N:18]([CH3:19])[C:11]1[CH2:12][CH2:13][CH2:14][N+:10]=1[CH:7]([CH3:9])[CH3:8]

참가 물질

4

반응물 2

HCID 674DimethylamineHCID 867369371-Isopropyl-2-methoxy-1-pyrrolinium methyl sulfate

생성물 1

HCID 1784564382-Dimethylamino-1-isopropyl-1-pyrrolinium methyl sulfate

시약·촉매·용매 1

HCID 241Benzene용매

실험 절차

161 g of 1-isopropyl-2-methoxy-1-pyrrolinium methyl sulfate are added dropwise, with stirring, to a solution of 43.8 g of dimethylamine in 283 ml of benzene. Subsequently, boiling under reflux is effected for 1.5 hours; the heavy phase is separated off and washed 4 times with, in each case, 50 ml of diethyl ether. After drying under a high vacuum, 154 g (91% of theory) of the title compound (as a reddish oil) are obtained.

후처리

  1. temperatureunder reflux
  2. customthe heavy phase is separated off
  3. washwashed 4 times with, in each case, 50 ml of diethyl ether
  4. dry with materialAfter drying under a high vacuum, 154 g (91% of theory) of the title compound (as a reddish oil)
  5. customare obtained

출처 및 근거

ORD 기록
ord-d7329244f675450cbe20abe886f84900
출처 데이터셋
uspto-grants-1980_04
특허 번호
US04198424

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