Tributylstannane → HCID 23466037, compound

Participants

Reaction Steps

To a solution of 200 mg of 3-hydroxy-3-methyl-4-bromo-7-phenyl-5-heptanolide in 2 ml of anhydrous tetrahydrofuran was added 500 mg of tri-n-butyltin hydride and the mixtue was allowed to stand overnight at room temperature. After completion of the reaction, tetrahydrofuran was evaporated and n-hexane was added to the residue to precipitate an oily substance, which was pruified by a thin layer chromatography (silica gel) affording 82 mg of the desired compound.

Provenance & Evidence