HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 3-(p-Acetylaminophenyl)-5-(4-pyridyl)-1,2,4-triazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 4-[5-(Pyridin-4-yl)-1H-1,2,4-triazol-3-yl]aniline | HCID 20285812 | — |
| Product | 3-(p-Acetylaminophenyl)-5-(4-pyridyl)-1,2,4-triazole | HCID 20285794 | — |
Reaction Steps
To 3-(p-aminophenyl)-5-(4-pyridyl)-1,2,4-triazole (1 g.) is added acetic anhydride (20 ml.) and the resulting suspension is heated 18 hours on a steam bath. The excess acetic anhydride is removed under reduced pressure and water (25 ml.) is added to the residue. After stirring 0.5 hour, the solid is filtered and recrystallized to yield 3-(p-acetylaminophenyl)-5-(4-pyridyl)-1,2,4-triazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04198513 |
| Source dataset | uspto-grants-1980_04 |
| ORD ID | ord-260b1b19076d438887b6b13692c93bcb |
| Source note | uspto-grants-1980_04 |