HCID 20344429, compound → HCID 20344436, compound

HRID 2049774Notes

Reaction equation

HRID 2049774 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][CH:9]([C:15]#[N:16])[CH2:10][C:11](OC)=[O:12]>[Ni]>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][CH:9]1[CH2:15][NH:16][C:11](=[O:12])[CH2:10]1

Participants

3

Reactant 1

HCID 20344429HCID 20344429, compound

Product 1

HCID 20344436HCID 20344436, compound

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

In the same manner as Example 1-(d), 10 g of methyl 4-(2-chlorophenyl)-3-cyanobutyrate was catalytically reduced with the aid of Raney's nickel to obtain 4-(2-chlorobenzyl)-2-pyrrolidinone.

Sources & evidence

ORD record
ord-0f53ac106f1c4f7eadbe36694729659d
Source dataset
uspto-grants-1980_04
Patent number
US04198514

Reaction notes

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