HCID 20344443, compound → HCID 20344427, compound

HRID 2049776Notes

Reaction equation

HRID 2049776 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH2:8][CH:9]([C:15]#[N:16])[CH2:10][C:11](OC)=[O:12])[CH:5]=[CH:6][CH:7]=1>[Ni]>[Cl:1][C:2]1[CH:3]=[C:4]([CH:5]=[CH:6][CH:7]=1)[CH2:8][CH:9]1[CH2:15][NH:16][C:11](=[O:12])[CH2:10]1

Participants

3

Reactant 1

HCID 20344443HCID 20344443, compound

Product 1

HCID 20344427HCID 20344427, compound

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

In the same manner as Example 1-(d), 5 g of methyl 4-(3-chlorophenyl)-3-cyanobutyrate was reduced with Raney's nickel as the catalyst to obtain 4-(3-chlorobenzyl)-2-pyrrolidinone.

Sources & evidence

ORD record
ord-8db890de23a14ebfa8f531e39e16805b
Source dataset
uspto-grants-1980_04
Patent number
US04198514

Reaction notes

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