Ethyl 2-bromopropionate → HCID 20344444, compound

HRID 2049778Notes

Reaction equation

HRID 2049778 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH:9]([C:15]#[N:16])[C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:4][CH:3]=1.Br[CH:18]([CH3:24])[C:19]([O:21][CH2:22][CH3:23])=[O:20]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][C:9]([C:15]#[N:16])([C:10]([O:12][CH2:13][CH3:14])=[O:11])[CH2:24][CH2:18][C:19]([O:21][CH2:22][CH3:23])=[O:20])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 79040Ethyl 2-bromopropionateHCID 10681376HCID 10681376, compound

Product 1

HCID 20344444HCID 20344444, compound

Procedure

In the same manner as Example 1-(b), 47.5 g of ethyl 3-(4-chlorophenyl)-2-cyanopropionate was reacted with ethyl 2-bromopropionate to obtain ethyl 5-(4-chlorophenyl)-4-cyano-4-ethoxycarbonylvalerate.

Sources & evidence

ORD record
ord-6c4271a836f84c889dd2c3dc81a144cf
Source dataset
uspto-grants-1980_04
Patent number
US04198514

Reaction notes

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