Ethyl bromoacetate → HCID 20344440, compound

HRID 2049780Notes

Reaction equation

HRID 2049780 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH:9]([C:15]#[N:16])[C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:4][CH:3]=1.Br[CH2:18][C:19]([O:21][CH2:22][CH3:23])=[O:20]>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][C:9]([C:15]#[N:16])([C:10]([O:12][CH2:13][CH3:14])=[O:11])[CH2:18][C:19]([O:21][CH2:22][CH3:23])=[O:20])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 7748Ethyl bromoacetateHCID 15946152HCID 15946152, compound

Product 1

HCID 20344440HCID 20344440, compound

Procedure

In the same manner as Example 1-(b), 100 g of ethyl 3-(4-fluorophenyl)-2-cyanopropionate was reacted with ethyl bromoacetate to obtain ethyl 4-(4-fluorophenyl)-3-cyano-3-ethoxycarbonylbutyrate.

Sources & evidence

ORD record
ord-67e58aa5a70642819153d1c1adf752be
Source dataset
uspto-grants-1980_04
Patent number
US04198514

Reaction notes

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