HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Acetylthio-2-methoxycarbonylmethylpropanoic acid → 1-[2-Carbamoylmethyl-3-acetylthiopropanoyl]-L-proline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Acetylthio-2-methoxycarbonylmethylpropanoic acid | HCID 12774428 | — |
| Reactant | 3-Acetylthio-2-carbamoylmethylpropanoic acid | HCID 20344453 | — |
| Reactant | 1-[2-(carbamoylmethyl)-3-(acetylthio)-propanyl]-L-proline | HCID 54523640 | — |
| Reactant | 1-[2-(carbamoylmethyl)-3-(acetylthio)propanoyl]-L-proline tert-butyl ester | HCID 86736944 | — |
| Product | 1-[2-Carbamoylmethyl-3-acetylthiopropanoyl]-L-proline | HCID 53761281 | — |
Reaction Steps
By substituting 3-acetylthio-2-(carbamoylmethyl)propanoic acid for the 3-(acetylthio)-2-(methoxycarbonylmethyl)-propanoic acid in the procedure of Example 2, and then submitting the product to the procedure of Example 3, 1-[2-(carbamoylmethyl)-3-(acetylthio)propanoyl]-L-proline tert-butyl ester and 1-[2-(carbamoylmethyl)-3-(acetylthio)-propanyl]-L-proline are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04198517 |
| Source dataset | uspto-grants-1980_04 |
| ORD ID | ord-72fa301c4c12404c911313bc8eefbc49 |
| Source note | uspto-grants-1980_04 |