HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Methoxide → Nalpha-[3-Mercapto-2-(methoxycarbonylmethyl)propanoyl]-L-arginine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | HCID 178500599 | HCID 178500599 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Nalpha-[3-Mercapto-2-(methoxycarbonylmethyl)propanoyl]-L-arginine | HCID 178500645 | — |
Reaction Steps
To a solution of Nα -[3-(acetylthio)-2-(methoxycarbonylmethyl)propanoyl]-L-arginine (1.9 g.) in methanol (10 ml.), sodium methoxide (0.56 g.) is added. After ten minutes, the solution is applied to a column of Dowex 50 resin and the column is washed with water until no more acidic material is eluted. Nα -[3-mercapto-2-(methoxycarbonylmethyl)propanoyl]-L-arginine is then eluted with a pyridine-acetate buffer of pH 6.5.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04198517 |
| Source dataset | uspto-grants-1980_04 |
| ORD ID | ord-1cc63d7b0cc24ba6aa69dc2125540c6f |
| Source note | uspto-grants-1980_04 |