HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl diazoacetate → 3-(4-Chlorophenoxy)-2,2-dimethylcyclopropanecarboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl diazoacetate | HCID 12192 | — |
| Reactant | Ethyl 3-(4-chlorophenoxy)-2,2-dimethylcyclopropanecarboxylate | HCID 20344552 | — |
| Reactant | 3-(4-Chlorophenoxy)-2-methyl-2-propene | HCID 20344578 | — |
| Catalyst | Copper | HCID 23978 | — |
| Product | 3-(4-Chlorophenoxy)-2,2-dimethylcyclopropanecarboxylic acid | HCID 20304961 | — |
Reaction Steps
Following the procedure of Example 1B, 7.2 g (0.040 mol) of 3-(4-chlorophenoxy)-2-methyl-2-propene and 0.2 g copper powder are reacted with 8.7 g (0.079 mol) ethyl diazoacetate to yeild ethyl 3-(4-chlorophenoxy)-2,2-dimethylcyclopropanecarboxylate, which is then hydrolyzed to give 3-(4-chlorophenoxy)-2,2-dimethylcyclopropanecarboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04198527 |
| Source dataset | uspto-grants-1980_04 |
| ORD ID | ord-6126c7b4137145c1bae69f176c16d211 |
| Source note | uspto-grants-1980_04 |