Ethyl diazoacetate → HCID 20344544, compound

Participants

Reaction Steps

2,2,2-Trifluoroethyl 2-methyl-1-propenyl ether (3.2 g) is combined, under nitrogen, with approx. 150 mg copper powder and heated to 130°. Ethyl diazoacetate (2.36 g) is very slowly added to the solution over 1.5 hr. The solution is then cooled and filtered, and the filtrate is washed with ether. The ether phase is distilled in vacuo to yield ethyl 3-(2,2,2-trifluoroethoxy)-2,2-dimethylcyclopropanecarboxylate.

Provenance & Evidence