Potassium Carbonate → HCID 20344577, compound

Participants

Reaction Steps

To 10 ml DMF is added 0.88 g 3-(2,2,2-trifluoroethoxy)-2,2-dimethylcyclopropanecarboxylic acid (4.l4 mmol) and 1.146 g potassium carbonate (8.29 mmol), after which is added 12 g m-phenoxybenzyl bromide. This mixture is stirred under nitrogen for 15 hr. The reaction mixture is extracted with ether and the ether phase is washed with water (3X) and brine, and dried over sodium sulfate. The solvent is then removed to yield m-phenoxybenzyl 3-(2,2,2-trifluoroethoxy)-2,2-dimethylcyclopropanecarboxylate, MS m/e 394.1 (M+).

Provenance & Evidence