Ethyl propiolate → HCID 54166829, compound

Participants

Reaction Steps

Using Example 15 procedures, ethyl propiolate and 4-fluorobenzenethiol are reacted, yielding ethyl 3-(4-fluorophenylthio)-2-propenoate. Three equiv. of this is then combined with 1 equiv. of phenyl(trifluoromethyl)mercury and 3 equiv. of dry powdered sodium iodide. This mixture is refluxed in benzene for 15-20 hr, then filtered and solvent is removed to give ethyl 3-(4-fluorophenylthio)-2,2-difluorocyclopropanecarboxylate.

Provenance & Evidence