Sodium Acetate → HCID 20344503, compound

HRID 2049847Notes

Reaction equation

HRID 2049847 reaction equation
C([O-])(=O)C.[Na+].Br.[C:7]([O:10][CH2:11][C:12]1[CH:17]=[CH:16][C:15]([NH:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])=[CH:14][CH:13]=1)(=[O:9])[CH3:8]>C(Cl)Cl>[C:7]([O:10][CH2:11][C:12]1[CH:13]=[CH:14][C:15]([NH:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])=[CH:16][CH:17]=1)(=[O:9])[CH3:8]

Participants

4

Reactant 2

HCID 517045Sodium AcetateHCID 20344518HCID 20344518, compound

Product 1

HCID 20344503HCID 20344503, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

One-half ml. of 30% aqueous sodium acetate is added to a solution of p-hexadecylaminobenzyl alcohol acetate hydrobromide (100 mg.) in methylene chloride (2 ml.). After thorough mixing, the organic layer is separated, dried over anhydrous sodium sulfate, and evaporated at ambient temperature to provide the product (50 mg.) of the Example, m.p. 43°-45° C.

Workup

  1. customAfter thorough mixing, the organic layer is separated
  2. dry with materialdried over anhydrous sodium sulfate
  3. customevaporated at ambient temperature
  4. customto provide the product (50 mg.) of the Example, m.p. 43°-45° C.

Sources & evidence

ORD record
ord-8a549f542a5242e59b65017094639c43
Source dataset
uspto-grants-1980_04
Patent number
US04198522

Reaction notes

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