HCID 54414003, compound → 6,8-Dimethylnonan-2-ol

HRID 2049855Notes

Reaction equation

HRID 2049855 reaction equation
[CH3:1][CH:2]([CH2:9][CH:10]([CH3:12])[CH3:11])[CH2:3][CH:4]=[CH:5][C:6](=[O:8])[CH3:7].[H][H]>[Cr]([O-])([O-])=O.[Cu+2]>[CH3:12][CH:10]([CH2:9][CH:2]([CH3:1])[CH2:3][CH2:4][CH2:5][CH:6]([OH:8])[CH3:7])[CH3:11]

Participants

4

Reactant 2

HCID 54414003HCID 54414003, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 1725016,8-Dimethylnonan-2-ol

Reagents, catalysts & solvents 1

HCID 178505374HCID 178505374, compoundCatalyst

Conditions

Temperature
170 °C

Procedure

64 g of the foregoing ketone are hydrogenated in a stirring autoclave in the presence of 6 g of copper chromite and under 40 bar hydrogen pressure. The temperature is firstly brought to 140° C. When the hydrogen absorption slows down (after 3 hours), the autoclave is heated to 170° C. and held for 3 hours between 165° C. and 170° C. After cooling down to 25° C., the catalyst is filtered off under suction and the filtrate is distilled. There are obtained 56 g (85.4%) of chemically pure 2,4-dimethyl-nonan-8-ol.

Workup

  1. customis firstly brought to 140° C
  2. customWhen the hydrogen absorption
  3. customslows down (after 3 hours)
  4. temperatureAfter cooling down to 25° C.
  5. filtrationthe catalyst is filtered off under suction
  6. distillationthe filtrate is distilled

Sources & evidence

ORD record
ord-4a2cc911d2d244e8b73f79fa9a701b74
Source dataset
uspto-grants-1980_04
Patent number
US04198532

Reaction notes

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