Hydrochloric Acid → 3-amino-4-chlorobenzenethiol

Participants

Reaction Conditions

Reaction Steps

To a mixture of 100 g of chipped ice and 120 g of concentrated hydrochloric acid (35%), 120 g of metallic tin was added and then 25.4 g of 3-nitro-4-chlorobenzenesulfonyl chloride was added thereto. The mixture was stirred for one and a half hours while maintaining the temperature at 0° C. Then, the temperature was increased to 80° C. to 90° C. and the mixture was stirred with heating at the same temperature for 2 hours. After the completion of the reaction, the reaction solution was kept for one day in a cold place (at about -5° C. to about 10° C.). The crystals formed were collected and thoroughly washed with water. From the water used for the washing and the filtrate, newly formed crystals were also recovered and were added to the first crystals obtained.

Provenance & Evidence