反应详情

To 25 milliliters of 2-methoxyethanol was added, with magnetic stirring, 5.0 grams (0.75 mole) of 85% potassium hydroxide pellets dissolved in 5 milliliters water. The amount of 5.0 grams (0.0216 mole) of 4-(chloromethyl)benzophenone was added, the mixture was refluxed for three hours, filtered with suction, and concentrated. Water was added and the oil which separated was isolated by extraction with ether to provide 5.0 grams (86% yield) of 4-(2-methoxyethoxymethyl)benzophenone as an orange colored liquid. Infrared analysis revealed the presence of a carbonyl band at 1660 cm-1. Ultraviolet analysis revealed λ max (ε) at 256 nanometers (18,380).

1. temperaturethe mixture was refluxed for three hours
2. filtrationfiltered with suction
3. concentrationconcentrated
4. additionWater was added
5. customthe oil which separated
6. customwas isolated by extraction with ether