HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 20298674, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 3-Chloro-N,N-dimethyl-1-propanamine | HCID 66960 | — |
| Reactant | 2-Hydroxy-5-methoxybenzaldehyde | HCID 95695 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 20298674 | HCID 20298674 | — |
Reaction Steps
2-Hydroxy-5-methoxybenzaldehyde (31.2 g) in 170 ml. of dimethylformamide is treated first with 10.1 g of 50% sodium hydride, then with 160 ml. of a 2 N toluene solution of 3-dimethylaminopropyl chloride, following the procedure described in Example 1A, yielding 34.1 g of the title compound, boiling point 149°-155° C. at 0.2-0.3 mm of Hg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04199528 |
| Source dataset | uspto-grants-1980_04 |
| ORD ID | ord-111da2d4f42d4aa9aa81b893dcdc1af1 |
| Source note | uspto-grants-1980_04 |