HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → 4-[3-[5-Methoxy-2-[[(2-phenylethyl)amino]methyl]phenoxy]propyl]morpholine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | HCID 20298685 | HCID 20298685 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-[3-[5-Methoxy-2-[[(2-phenylethyl)amino]methyl]phenoxy]propyl]morpholine | HCID 20298683 | 77.8% |
Reaction Steps
4-[3-[5-Methoxy-2-[[(2-phenylethyl)imino]-methyl]phenoxy]propyl]morpholine (33 g) is reduced with 9.8 g of sodium borohydride in 150 ml. of methanol following the procedure described in Example 1C, yielding 25.8 g of the title compound, boiling point 249°-254° C. at 0.3-0.4 mm of Hg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04199528 |
| Source dataset | uspto-grants-1980_04 |
| ORD ID | ord-f07a4961dc5d4cee985527e5275a1ba8 |
| Source note | uspto-grants-1980_04 |