HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium cyanoborohydride → HCID 20556403, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium cyanoborohydride | HCID 5003444 | — |
| Reactant | HCID 53642397 | HCID 53642397 | — |
| Reactant | HCID 86736553 | HCID 86736553 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 20556403 | HCID 20556403 | — |
Reaction Steps
The 3,4-dichloro-N-[2-oxocycloheptyl]propionanilide from Part C above is treated with sodium cyanoborohydride and dimethylamine-dimethylamine hydrochloride in methanol in the presence of 3 A molecular sieves; the resulting mixture is worked up under basic pH conditions and the organic residue is chromatographed (column) on silica gel to isolate the cis isomer of 3,4-dichloro-N-[2-(dimethylamino)cycloheptyl]propionanilide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04199589 |
| Source dataset | uspto-grants-1980_04 |
| ORD ID | ord-b314d6f9c42d496f8ae8132577e3a9bb |
| Source note | uspto-grants-1980_04 |