2-[4-(Dimethylamino)benzoyl]benzoic acid → HCID 20392472, compound

HRID 2050114Notes

Reaction equation

HRID 2050114 reaction equation
[CH3:1][N:2]([CH3:20])[C:3]1[CH:19]=[CH:18][C:6]([C:7]([C:9]2[CH:17]=[CH:16][CH:15]=[CH:14][C:10]=2[C:11]([OH:13])=[O:12])=O)=[CH:5][CH:4]=1.[C:21]([NH:24][C:25]1[CH:37]=[CH:36][C:28]([NH:29][C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)=[CH:27][CH:26]=1)(=[O:23])[CH3:22]>>[CH3:20][N:2]([CH3:1])[C:3]1[CH:4]=[CH:5][C:6]([C:7]2([N:29]([C:30]3[CH:31]=[CH:32][CH:33]=[CH:34][CH:35]=3)[C:28]3[CH:27]=[CH:26][C:25]([NH:24][C:21](=[O:23])[CH3:22])=[CH:37][CH:36]=3)[C:9]3[C:10](=[CH:14][CH:15]=[CH:16][CH:17]=3)[C:11](=[O:12])[O:13]2)=[CH:18][CH:19]=1

Participants

3

Reactant 2

HCID 889372-[4-(Dimethylamino)benzoyl]benzoic acidHCID 78963538674-90-7

Product 1

HCID 20392472HCID 20392472, compoundYield 83.2%

Procedure

Following a procedure similar to that described in Example 1 but employing 4.0 g of 2-[4-(dimethylamino)benzoyl]benzoic acid and 3.4 g of 4-acetamido-N-phenylaniline there was obtained 5.9 g of 3-[4-(dimethylamino)phenyl]-3-[N-(4-acetamidophenyl)phenylamino]phthalide, m.p. 182°-184.5° C. An acetone solution of the product contacted with acidic clay or phenolic resin developed an orange-colored image.

Sources & evidence

ORD record
ord-81d8cb5916b344f4a97c0d9b2ddd25c3
Source dataset
uspto-grants-1980_04
Patent number
US04200313

Reaction notes

Loading…