63966-94-9 → HCID 20341832, compound

HRID 2050131Notes

Reaction equation

HRID 2050131 reaction equation
[CH2:1]([CH:19]1[CH2:24][C:23](=[O:25])[N:22]([C:26]2[CH:31]=[CH:30][C:29]([N+:32]([O-])=O)=[CH:28][C:27]=2[OH:35])[C:20]1=[O:21])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[H][H]>C(O)C.[Pd]>[CH2:1]([CH:19]1[CH2:24][C:23](=[O:25])[N:22]([C:26]2[CH:31]=[CH:30][C:29]([NH2:32])=[CH:28][C:27]=2[OH:35])[C:20]1=[O:21])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

Participants

5

Reactant 2

HCID 418257663966-94-9HCID 178418361HCID 178418361, compound

Product 1

HCID 20341832HCID 20341832, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalyst2×HCID 702EthanolSolvent

Procedure

In 2 liters of ethanol were suspended 150 g of 2-octadecylsuccinimido-5-nitro-phenol and 7.5 g of palladium/carbon were added to the suspension, which was subjected to catalytic reduction with hydrogen gas at room temperature under normal pressure. After about 10 hours of reaction period of time, palladium/carbon was filtered off and ethanol was removed by distillation. The residue was recrystallized from benzene to give white powdery crystal melting at 85°-90° C. in the yield of 90 g.

Workup

  1. additionwere added to the suspension, which
  2. filtrationwas filtered off
  3. customethanol was removed by distillation
  4. customThe residue was recrystallized from benzene

Sources & evidence

ORD record
ord-a03a28ef56b641dbb7c66ede199ef7d0
Source dataset
uspto-grants-1980_04
Patent number
US04200466

Reaction notes

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